Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
Microsoft Image Extension
image/vnd.mix
MIX
A complete technical comparison of DICOM Run-Length Encoding and Microsoft Image Extension — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | MIX |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Microsoft Image Extension
image/vnd.mix
Extension
.mix
Container
Microsoft OLE Structured Storage (COM)
Compression
Proprietary (Internal JPEG/RLE)
Algorithm
JPEGDeflateProprietary
Color Depth
8-bit, 24-bit, 32-bit (RGBA)
Developed by
Microsoft Corporation
Released
1996
Magic Bytes
D0 CF 11 E0 A1 B1 1A E1
Browser Support Comparison
| Browser | DICOM-RLE | MIX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
MIX
MIX Strengths
- Allowed early consumer software to non-destructively edit complex compositions involving photos, text, and vector clipart
- Shared an architecture with other Microsoft Office products, enabling deep integration (OLE embedding) into Word and PowerPoint at the time
Limitations
- Completely proprietary and undocumented, leading to a massive loss of historical data for users who archived their family photos in this project format
- Requires traversing a complex OLE filesystem just to extract the flattened raster image
- No support in modern image editors like Photoshop, GIMP, or web browsers
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
MIX
Use MIX when…
- Historical Microsoft Picture It! Projects
- Microsoft PhotoDraw 2000 Graphics
- Early 2000s Consumer Digital Scrapbooking