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Image MIME Reference
PCO-B16

PCO B16 Image

image/vnd.pco.b16
VS

Windows Metafile

image/x-wmf
WMF

A complete technical comparison of PCO B16 Image and Windows Metafile — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature PCO-B16 WMF
Transparency (Alpha) ✕ No Yes
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support ✕ No ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile ✕ No ✕ No
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →
Windows Metafile
image/x-wmf
Extension
.wmf.emf
Container Windows GDI Metafile Command Stream
Compression Uncompressed (Command Stream)
Algorithm
None
Color Depth Varies based on GDI rendering engine
Developed by Microsoft Corporation
Released 1990
Magic Bytes
D7 CD C6 9A (Aldus Placeable Metafile Header) or 01 00 09 00 (Standard WMF Header)
Full WMF reference →

Browser Support Comparison

Browser PCO-B16 WMF
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer
WMF

WMF Strengths

  • Infinitely scalable vector format that remains remarkably compact for simple geometric illustrations and charts
  • Historically served as a seamless conduit for copying and pasting vector graphics between disparate Windows applications via the system clipboard
Limitations
  • Notoriously plagued by historic security vulnerabilities, making raw WMF parsing a vector for exploits in legacy software
  • Completely obsolete and unsupported in modern web environments (browsers cannot render them)
  • Strictly tied to the Windows GDI architecture, making cross-platform rendering inconsistent across Linux and macOS

When to choose which format

PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
WMF
Use WMF when…
  • Legacy Microsoft Office Clip Art and Icons
  • Windows GDI Graphics Export
  • Early Windows Desktop Publishing
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