Image MIME Reference
PCO-B16
PCO B16 Image
image/vnd.pco.b16
VS
TIFF for Facsimile eXtended
image/tiff-fx
TIFF-FX
A complete technical comparison of PCO B16 Image and TIFF for Facsimile eXtended — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | PCO-B16 | TIFF-FX |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | ✕ No | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | ✕ No | Yes |
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
TIFF for Facsimile eXtended
image/tiff-fx
Extension
.tiff.tif
Container
TIFF 6.0 Tag Directory Structure
Compression
MH / MR / MMR (CCITT Group 3 & 4) / JBIG / JPEG
Algorithm
CCITT Group 3/4JBIGJPEG
Color Depth
1-bit (Monochrome B&W), 8-bit (Grayscale/Color Indexed), 24-bit (RGB Color)
Developed by
IETF (Internet Engineering Task Force)
Released
1998
Magic Bytes
49 49 2A 00 (Little-Endian) / 4D 4D 00 2A (Big-Endian)
Browser Support Comparison
| Browser | PCO-B16 | TIFF-FX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
TIFF-FX
TIFF-FX Strengths
- Provides a universal, standardized format for transmitting multi-page documents over IP networks and email (Internet Fax)
- Supports highly efficient telecom-centric compression algorithms (MMR, JBIG) that produce very small files for text documents
- Maintains backwards compatibility with standard TIFF parsers
Limitations
- Not supported natively by web browsers
- Requires complex parsing of TIFF IFD tags to differentiate a true TIFF-FX file from a standard TIFF file
- Usage is slowly declining as traditional faxing is replaced by secure PDF transmission and e-signature platforms
When to choose which format
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry
TIFF-FX
Use TIFF-FX when…
- Internet Fax (T.37)
- Enterprise Fax Servers
- Document Archiving
- Telecommunications