Free webp to jpg
Image MIME Reference
PCO-B16

PCO B16 Image

image/vnd.pco.b16
VS

T.38 Fax over IP (FoIP)

image/t38
T.38

A complete technical comparison of PCO B16 Image and T.38 Fax over IP (FoIP) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature PCO-B16 T.38
Transparency (Alpha) ✕ No ✕ No
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support ✕ No ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile ✕ No ✕ No
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →
T.38 Fax over IP (FoIP)
image/t38
Extension
.t38
Container UDPTL or TCP (Network Transport)
Compression Lossless (MH, MR, MMR / T.4, T.6)
Algorithm
MH (Modified Huffman)MR (Modified Read)MMR (Modified Modified Read)
Color Depth 1-bit (Monochrome B&W)
Developed by ITU-T (International Telecommunication Union)
Released 1998
Magic Bytes
None (Network Stream)
Full T.38 reference →

Browser Support Comparison

Browser PCO-B16 T.38
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer
T.38

T.38 Strengths

  • Designed specifically to overcome the timing and packet-loss issues that plague traditional fax over standard VoIP audio codecs (like G.711)
  • Reduces bandwidth requirements by transmitting fax protocol data rather than uncompressed audio tones
  • Universally supported by enterprise SIP trunks and Session Border Controllers (SBCs) for FoIP
Limitations
  • Not an actual image file format, causing confusion due to its 'image/' MIME classification
  • Extremely complex to implement correctly over lossy UDP networks (relies on UDPTL redundancy mechanisms)
  • Zero support in web browsers or standard image viewing software

When to choose which format

PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
T.38
Use T.38 when…
  • Fax over IP (FoIP) Transmissions
  • SIP/SDP Media Negotiation
  • VoIP Gateways and PBX Systems
  • Enterprise Fax Servers
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