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Image MIME Reference
PCO-B16

PCO B16 Image

image/vnd.pco.b16
VS

Sigma X3F RAW Image

image/x-sigma-x3f
Sigma-X3F

A complete technical comparison of PCO B16 Image and Sigma X3F RAW Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature PCO-B16 Sigma-X3F
Transparency (Alpha) ✕ No ✕ No
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support ✕ No Yes
EXIF Metadata ✕ No Yes
ICC Color Profile ✕ No Yes
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →
Sigma X3F RAW Image
image/x-sigma-x3f
Extension
.x3f
Container Foveon Proprietary Header
Compression Uncompressed / Proprietary Lossless
Algorithm
NoneFoveon Proprietary Huffman-based
Color Depth 12-bit (Per Channel), 14-bit (Per Channel)
Developed by Foveon, Inc. / Sigma Corporation
Released 2002
Magic Bytes
46 4F 56 62
Full Sigma-X3F reference →

Browser Support Comparison

Browser PCO-B16 Sigma-X3F
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer
Sigma-X3F

Sigma-X3F Strengths

  • Provides absolute per-pixel color accuracy without the interpolation artifacts or moiré patterns typical of Bayer-sensor RAW files
  • Unique 'FOVb' magic byte signature prevents accidental misidentification by standard file sniffers, unlike many TIFF-based raw formats
  • Incredible sharpness and detail resolution at the raw sensor level
Limitations
  • Decoding is extremely computationally expensive and completely proprietary, meaning third-party software often struggles to match the color science of Sigma's own (famously slow) Photo Pro application
  • Massive file sizes because it records three complete RGB channels for every single spatial pixel coordinate
  • Zero support in web browsers or standard OS image viewers

When to choose which format

PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
Sigma-X3F
Use Sigma-X3F when…
  • Professional Digital Photography
  • Sigma / Foveon High-Acuity Imaging
  • Non-destructive RAW Post-Processing
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