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Image MIME Reference
PCO-B16

PCO B16 Image

image/vnd.pco.b16
VS

PTI Image (Personal/Vanity Tree)

image/prs.pti
PTI

A complete technical comparison of PCO B16 Image and PTI Image (Personal/Vanity Tree) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature PCO-B16 PTI
Transparency (Alpha) ✕ No ✕ No
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support ✕ No ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile ✕ No ✕ No
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →
PTI Image (Personal/Vanity Tree)
image/prs.pti
Extension
.pti
Container Proprietary
Compression Unknown / Proprietary
Algorithm
Unknown
Color Depth Unknown
Developed by Jürn Laun
Released 1999
Magic Bytes
Unknown
Full PTI reference →

Browser Support Comparison

Browser PCO-B16 PTI
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer
PTI

PTI Strengths

  • Provided a registered MIME type namespace for a specific application's proprietary image format without conflicting with standard web types
Limitations
  • Completely undocumented and unsupported in modern ecosystems
  • Zero web browser compatibility
  • Falls into the 'vanity' tree, making it irrelevant for standard cross-platform data exchange

When to choose which format

PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
PTI
Use PTI when…
  • Legacy Application Specific Workflows
  • Proprietary Image Storage
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