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Image MIME Reference
PCO-B16

PCO B16 Image

image/vnd.pco.b16
VS

Portable Anymap

image/x-portable-anymap
PNM

A complete technical comparison of PCO B16 Image and Portable Anymap — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature PCO-B16 PNM
Transparency (Alpha) ✕ No ✕ No
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support ✕ No ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile ✕ No ✕ No
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →
Portable Anymap
image/x-portable-anymap
Extension
.pnm
Container Netpbm
Compression Uncompressed
Algorithm
None
Color Depth 1-bit (PBM), 8-bit to 16-bit (PGM), 24-bit to 48-bit (PPM)
Developed by Jef Poskanzer (Netpbm Project)
Released 1988
Magic Bytes
50 31, 50 32, 50 33, 50 34, 50 35, or 50 36
Full PNM reference →

Browser Support Comparison

Browser PCO-B16 PNM
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer
PNM

PNM Strengths

  • Unparalleled simplicity: parsers and writers for PNM files can be written from scratch in C or Python in just a few minutes without relying on external libraries
  • Serves as an excellent foundational teaching tool for computer science students learning about image arrays and raster graphics
  • Flawlessly pipes through Unix command-line utilities for robust automated image processing (via the Netpbm suite)
Limitations
  • Zero compression natively results in astronomical file sizes, making it entirely impractical for web delivery or consumer storage
  • No support for standard metadata formats like EXIF, XMP, or ICC color profiles
  • No native alpha channel support in the classic PNM specification (though the newer PAM format 'P7' addresses this)

When to choose which format

PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
PNM
Use PNM when…
  • Unix/Linux Command-Line Image Processing (Netpbm suite)
  • Academic Computer Vision Research
  • Intermediary Format for Image Format Conversion
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