Image MIME Reference
PCO-B16
PCO B16 Image
image/vnd.pco.b16
VS
PiCture eXchange
image/x-pcx
PCX
A complete technical comparison of PCO B16 Image and PiCture eXchange — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | PCO-B16 | PCX |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | ✕ No | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | ✕ No | ✕ No |
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
PiCture eXchange
image/x-pcx
Extension
.pcx
Container
ZSoft Proprietary Header (128 bytes)
Compression
Run-Length Encoding (RLE)
Algorithm
ZSoft RLE
Color Depth
1-bit (Monochrome), 4-bit (16 colors), 8-bit (256 colors), 24-bit (True Color)
Developed by
ZSoft Corporation
Released
1985
Magic Bytes
0A (followed by version, e.g., 0A 05 01 08)
Browser Support Comparison
| Browser | PCO-B16 | PCX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
PCX
PCX Strengths
- Incredibly simple RLE algorithm makes it very fast to decode, which was historically vital for early 3D video game engines
- Retains crisp, lossless pixel data suitable for pixel art and interface assets
- Well-documented and highly supported by older desktop publishing and image editing software
Limitations
- Extremely inefficient compression by modern standards, producing large file sizes compared to PNG
- Lacks modern imaging features such as alpha channel transparency, EXIF metadata, and color profiles
- Zero support in web browsers; must be converted to PNG for web use
When to choose which format
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry
PCX
Use PCX when…
- MS-DOS and Early Windows Graphics
- 1990s Video Game Assets (Textures, UI)
- Retro Computing Archival