Image MIME Reference
Net-FPX
Network FlashPix
image/vnd.net-fpx
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of Network FlashPix and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | Net-FPX | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | Yes | ✕ No |
| HDR Support | ✕ No | ✕ No |
| EXIF Metadata | Yes | ✕ No |
| ICC Color Profile | Yes | ✕ No |
Network FlashPix
image/vnd.net-fpx
Extension
.fpx
Container
Microsoft OLE Structured Storage (COM)
Compression
JPEG (Lossy) / Uncompressed / Single-color (Solid)
Algorithm
JPEGNone
Color Depth
8-bit (Grayscale/Indexed), 24-bit (RGB), 32-bit (CMYK/RGBA)
Developed by
Digital Imaging Group (Kodak, HP, Live Picture, Microsoft)
Released
1996
Magic Bytes
D0 CF 11 E0 A1 B1 1A E1
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | Net-FPX | PCO-B16 |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
Net-FPX
Net-FPX Strengths
- Revolutionized web imaging in the late 1990s by proving that massive gigapixel images could be navigated seamlessly over 56k dial-up modems
- Pioneered the tile-based, multi-resolution pyramid concepts that eventually evolved into modern standards like IIIF (International Image Interoperability Framework)
Limitations
- Completely obsolete, having been replaced by standard JPEG servers and modern tiling formats like Deep Zoom or JPEG 2000/XR
- Relied on proprietary Java applets or ActiveX controls to render the tiles dynamically in a web browser
- Extremely complex to parse server-side due to the heavy OLE filesystem container
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
Net-FPX
Use Net-FPX when…
- Historical Internet Imaging Protocol (IIP) Streaming
- Early E-Commerce Deep Zoom Implementations
- Legacy High-Resolution Image Servers
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry