Image MIME Reference
JPEG-XS-Sequence
JPEG XS Image Sequence (HEIF Container)
image/jxss
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of JPEG XS Image Sequence (HEIF Container) and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | JPEG-XS-Sequence | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | Yes | ✕ No |
| ICC Color Profile | Yes | ✕ No |
JPEG XS Image Sequence (HEIF Container)
image/jxss
Extension
.jxss.jxs
Container
HEIF / ISOBMFF (ISO/IEC 23008-12)
Compression
Lossy (Visually Lossless) / Mathematically Lossless
Algorithm
JPEG XS (ISO/IEC 21122-1)
Color Depth
8-bit, 10-bit, 12-bit, 14-bit, 16-bit
Developed by
Joint Photographic Experts Group (JPEG)
Released
2019
Magic Bytes
XX XX XX XX 66 74 79 70 6A 78 73 73
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | JPEG-XS-Sequence | PCO-B16 |
|---|---|---|
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
JPEG-XS-Sequence
JPEG-XS-Sequence Strengths
- Provides sub-millisecond encoding and decoding latency across a video sequence while retaining visually lossless quality
- Leverages the robust ISOBMFF track structures for accurate frame timing, audio synchronization, and metadata handling
- Optimized for professional video production and IP broadcasting workflows
Limitations
- Zero web browser compatibility, limiting its use entirely to professional and industrial hardware workflows
- Compression ratios are significantly lower than consumer video codecs like HEVC or AV1
- Extremely niche format that requires highly specialized broadcast hardware or custom software libraries to process
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
JPEG-XS-Sequence
Use JPEG-XS-Sequence when…
- Live Broadcast Video Snippets
- Medical Imaging Sequences
- HDR Burst Photography Archiving
- Automotive & Drone Video Storage
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry