Image MIME Reference
JPEG-LS
JPEG-LS
image/jls
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of JPEG-LS and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | JPEG-LS | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | ✕ No | ✕ No |
JPEG-LS
image/jls
Extension
.jls.jl
Container
JPEG Bitstream
Compression
Lossless / Near-Lossless (Predictive Coding)
Algorithm
LOCO-I (Low Complexity Lossless Compression for Images)Golomb-Rice Coding
Color Depth
8-bit, 12-bit, 16-bit (Per Channel)
Developed by
Joint Photographic Experts Group (ISO/ITU-T) & HP Labs
Released
1999
Magic Bytes
FF D8 FF F7
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | JPEG-LS | PCO-B16 |
|---|---|---|
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
JPEG-LS
JPEG-LS Strengths
- Provides state-of-the-art lossless compression ratios for continuous-tone images, often outperforming Lossless JPEG and JPEG 2000
- Extremely fast and computationally inexpensive to encode/decode, requiring no complex floating-point math or DCTs
- Highly resilient in constrained hardware environments, making it ideal for medical equipment and deep-space probes (e.g., Mars rovers)
Limitations
- Zero native support in web browsers or standard consumer operating systems
- Lacks the advanced resolution scalability and progressive decoding features found in JPEG 2000
- Primarily relegated to niche enterprise sectors (healthcare/DICOM and aerospace) rather than consumer adoption
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
JPEG-LS
Use JPEG-LS when…
- Medical Imaging (DICOM Encapsulation)
- Space and Planetary Imaging (NASA/ESA)
- Industrial Machine Vision
- Scientific Archival Storage
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry