Image MIME Reference
JPEG-2000
JPEG 2000 Core Image File
image/jp2
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of JPEG 2000 Core Image File and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
JPEG-2000 wins on browser support
Feature Support
| Feature | JPEG-2000 | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | Yes | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | Yes | ✕ No |
| ICC Color Profile | Yes | ✕ No |
JPEG 2000 Core Image File
image/jp2
Extension
.jp2.j2k.jpf.jpx.jpm
Container
JP2 (ISO/IEC 15444-1)
Compression
Lossy / Lossless
Algorithm
Discrete Wavelet Transform (DWT)
Color Depth
8-bit, 16-bit, 32-bit, 38-bit
Developed by
Joint Photographic Experts Group
Released
2000
Magic Bytes
00 00 00 0C 6A 50 20 20 0D 0A 87 0A
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | JPEG-2000 | PCO-B16 |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✓ 5+
|
✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
JPEG-2000
JPEG-2000 Strengths
- Superior compression efficiency over baseline JPEG without introducing blocking artifacts
- True mathematically lossless compression available in the same format
- Extremely scalable: a single file can be decoded at various resolutions (thumbnails to full size) without loading the entire file
Limitations
- Very poor native web browser support prevents it from being a web standard
- High computational complexity makes encoding and decoding significantly slower than JPEG
- Early patent concerns and complex licensing hindered its initial adoption rate
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
JPEG-2000
Use JPEG-2000 when…
- Digital Cinema (DCP)
- Medical Imaging (DICOM)
- Geospatial Data
- Archival Preservation
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry