Image MIME Reference
HEJ2K
JPEG 2000 Image (HEIF Container)
image/hej2k
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of JPEG 2000 Image (HEIF Container) and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | HEJ2K | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | ✕ No | ✕ No |
| Progressive Loading | Yes | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | Yes | ✕ No |
| ICC Color Profile | Yes | ✕ No |
JPEG 2000 Image (HEIF Container)
image/hej2k
Extension
.hej2
Container
HEIF / ISOBMFF (ISO/IEC 15444-16)
Compression
Lossy / Lossless
Algorithm
JPEG 2000HTJ2K
Color Depth
8-bit, 10-bit, 12-bit, 16-bit
Developed by
ISO/IEC JTC 1 / ITU-T
Released
2019
Magic Bytes
XX XX XX XX 66 74 79 70 6A 32 6B 69
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | HEJ2K | PCO-B16 |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
HEJ2K
HEJ2K Strengths
- Brings the extensive capabilities of the HEIF container (like EXIF/XMP, thumbnails, and depth maps) to JPEG 2000
- Supports mathematically lossless compression via wavelet transformation
- High scalability and progressive decoding out of the box
Limitations
- Extremely limited software support outside of niche industries
- Zero native compatibility with web browsers
- High computational complexity compared to simpler formats like JPEG or PNG
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
HEJ2K
Use HEJ2K when…
- Medical Imaging
- Geospatial Data
- Scientific Archiving
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry