Image MIME Reference
FLIF
Free Lossless Image Format
image/flif
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of Free Lossless Image Format and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | FLIF | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | Yes | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | Yes | ✕ No |
| ICC Color Profile | Yes | ✕ No |
Free Lossless Image Format
image/flif
Extension
.flif
Container
FLIF Bitstream
Compression
Lossless (MANIAC Entropy Coding)
Algorithm
MANIAC (Meta-Adaptive Near-zero Integer Arithmetic Coding)
Color Depth
1-bit to 16-bit (Per Channel), Grayscale, RGB, RGBA, CMYK
Developed by
Jon Sneyers and Pieter Wuille (Cloudinary)
Released
2015
Magic Bytes
46 4C 49 46
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | FLIF | PCO-B16 |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
FLIF
FLIF Strengths
- Achieves some of the highest lossless compression ratios ever developed for raster images
- Incredible progressive decoding allows an image to be highly recognizable even after only 5% of the file has been downloaded
- Supports animations and complex alpha channels losslessly
Limitations
- Officially abandoned in favor of JPEG XL
- Zero native support in web browsers or standard operating system previewers
- Encoding speed can be significantly slower than standard PNG or WebP compression
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
FLIF
Use FLIF when…
- Archival of Uncompressed Image Assets
- Bandwidth-Constrained Progressive Image Loading (Historical)
- Medical and Scientific Imaging Storage
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry