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Image MIME Reference
FITS

Flexible Image Transport System

image/fits
VS

PCO B16 Image

image/vnd.pco.b16
PCO-B16

A complete technical comparison of Flexible Image Transport System and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature FITS PCO-B16
Transparency (Alpha) ✕ No ✕ No
Animation Support ✕ No ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile ✕ No ✕ No
Flexible Image Transport System
image/fits
Extension
.fits.fit.fts
Container FITS
Compression Uncompressed / Tile Compressed (Rice, GZIP)
Algorithm
UncompressedRiceGZIPHcompress
Color Depth 8-bit, 16-bit, 32-bit, 64-bit (Float/Double)
Developed by IAU FITS Working Group / NASA
Released 1981
Magic Bytes
53 49 4D 50 4C 45 20 20 3D 20
Full FITS reference →
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container PCO B16 Binary Container
Compression Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth 16-bit (Monochrome or Bayer Raw Color)
Developed by PCO AG (Excelitas PCO GmbH)
Released Early 2000s
Magic Bytes
50 43 4F 2D
Full PCO-B16 reference →

Browser Support Comparison

Browser FITS PCO-B16
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
FITS

FITS Strengths

  • The undisputed global standard for archiving and sharing astronomical data
  • Self-documenting: Headers are written in plain ASCII, ensuring data is readable decades later regardless of software
  • Supports incredibly high dynamic range, N-dimensional arrays, and complex binary tables
Limitations
  • No support in standard consumer software or web browsers
  • Uncompressed raw FITS files from modern telescopes can be excessively large
  • Does not use standard metadata models like EXIF or XMP, requiring specialized parsers
PCO-B16

PCO-B16 Strengths

  • Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
  • The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
  • Generates massive file sizes due to the complete lack of image compression [1.3.1]
  • Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
  • Strictly tied to the hardware and software ecosystems of a single camera manufacturer

When to choose which format

FITS
Use FITS when…
  • Astronomy & Astrophysics
  • Space Telescope Data (Hubble, JWST)
  • Scientific Data Archiving
  • Spectroscopy
PCO-B16
Use PCO-B16 when…
  • Microscopy and Life Sciences
  • High-Speed Camera Recording
  • Machine Vision and Industrial Inspection
  • Scientific Photometry
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