Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
JPEG XR Image (HEIF Container)
image/jxra
JPEG-XR-(HEIF)
A complete technical comparison of DICOM Run-Length Encoding and JPEG XR Image (HEIF Container) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | JPEG-XR-(HEIF) |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | Yes |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
JPEG XR Image (HEIF Container)
image/jxra
Extension
.jxra
Container
HEIF / ISOBMFF (ISO/IEC 23008-12 / Annex F of ITU-T T.832)
Compression
Lossy / Lossless
Algorithm
JPEG XR (Lapped Biorthogonal Transform)
Color Depth
8-bit, 16-bit, 32-bit (Float)
Developed by
ISO/IEC JTC 1 / ITU-T
Released
2019
Magic Bytes
XX XX XX XX 66 74 79 70 6A 78 72 41
Browser Support Comparison
| Browser | DICOM-RLE | JPEG-XR-(HEIF) |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JPEG-XR-(HEIF)
JPEG-XR-(HEIF) Strengths
- Combines the deep color (32-bit float) and mathematically lossless compression of JPEG XR with the robust metadata architecture of HEIF
- Allows grouping multiple images, exposure brackets, or focal stacks into a single file collection
Limitations
- Practically non-existent software and operating system support compared to standard HEIC or legacy JPEG XR (.jxr)
- Zero web browser support, rendering it entirely unsuitable for public web deployment
- Eclipsed by modern standards like AVIF and JPEG XL which offer superior compression with much broader industry backing
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
JPEG-XR-(HEIF)
Use JPEG-XR-(HEIF) when…
- Specialized Archival
- Experimental Imaging Workflows
- High Dynamic Range (HDR) Imaging