Image MIME Reference
CLIP
Clip Studio Paint Document
image/vnd.clip
VS
PCO B16 Image
image/vnd.pco.b16
PCO-B16
A complete technical comparison of Clip Studio Paint Document and PCO B16 Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | CLIP | PCO-B16 |
|---|---|---|
| Transparency (Alpha) | Yes | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | ✕ No | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | Yes | ✕ No |
Clip Studio Paint Document
image/vnd.clip
Extension
.clip.lip
Container
SQLite 3 Database
Compression
Proprietary Blob Compression (within SQLite)
Algorithm
Proprietary (Celsys Blob Encoding)
Color Depth
8-bit (Monochrome), 8-bit (Grayscale), 24-bit (RGB), 32-bit (CMYK)
Developed by
Celsys, Inc.
Released
2012
Magic Bytes
53 51 4C 69 74 65 20 66 6F 72 6D 61 74 20 33 00
PCO B16 Image
image/vnd.pco.b16
Extension
.b16
Container
PCO B16 Binary Container
Compression
Uncompressed (Raw Sensor Data)
Algorithm
None
Color Depth
16-bit (Monochrome or Bayer Raw Color)
Developed by
PCO AG (Excelitas PCO GmbH)
Released
Early 2000s
Magic Bytes
50 43 4F 2D
Browser Support Comparison
| Browser | CLIP | PCO-B16 |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
CLIP
CLIP Strengths
- SQLite backend provides incredibly robust data integrity, preventing catastrophic project loss if the application crashes during a save
- Allows for massive multi-page comic projects and animation timelines to be handled efficiently without loading the entire project into RAM simultaneously
- Industry standard for manga, anime, and webtoon professional workflows
Limitations
- Heavily closed-source and proprietary, meaning no third-party applications (like ImageMagick or GIMP) can parse or render the files
- Standard MIME identification tools will misidentify the file as a generic SQLite database, causing friction in automated file-upload validations
- Zero web browser support
PCO-B16
PCO-B16 Strengths
- Preserves exact, uncompressed 16-bit raw sensor data, which is critically important for accurate scientific measurements, fluorescence microscopy, and photometry
- The simple, linear struct header is highly predictable and easy to parse in custom Python, MATLAB, or C++ scripts for researchers building bespoke pipelines
Limitations
- Generates massive file sizes due to the complete lack of image compression [1.3.1]
- Completely unsupported by standard operating systems, web browsers, and consumer image editing suites
- Strictly tied to the hardware and software ecosystems of a single camera manufacturer
When to choose which format
CLIP
Use CLIP when…
- Digital Illustration and Concept Art
- Manga and Webtoon Production
- 2D Frame-by-Frame Animation
- High-Resolution Print Production
PCO-B16
Use PCO-B16 when…
- Microscopy and Life Sciences
- High-Speed Camera Recording
- Machine Vision and Industrial Inspection
- Scientific Photometry