Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
Pixologic ZBrush PCX
image/vnd.zbrush.pcx
ZBrush-PCX
A complete technical comparison of DICOM Run-Length Encoding and Pixologic ZBrush PCX — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | ZBrush-PCX |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | Yes | ✕ No |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Pixologic ZBrush PCX
image/vnd.zbrush.pcx
Extension
.pcx
Container
ZSoft PCX
Compression
Run-Length Encoding (RLE)
Algorithm
ZSoft Run-Length Encoding (RLE)
Color Depth
8-bit (Grayscale), 24-bit (RGB)
Developed by
ZSoft (Format) / Pixologic (MIME Registration)
Released
1985
Magic Bytes
0A 05 01 08
Browser Support Comparison
| Browser | DICOM-RLE | ZBrush-PCX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
ZBrush-PCX
ZBrush-PCX Strengths
- Extremely simple, lossless RLE compression makes it trivial to parse and encode programmatically
- Universally supported by almost every 2D image editor created since the 1990s
Limitations
- Completely obsolete for modern 3D workflows, which require 16-bit or 32-bit floating-point precision (like OpenEXR or TIFF) to avoid stepping artifacts in displacement maps
- No support for modern metadata (EXIF/XMP) or native alpha channels
- Zero native support in modern web browsers
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
ZBrush-PCX
Use ZBrush-PCX when…
- Legacy ZBrush Alpha Brushes
- 8-bit Grayscale Displacement Maps
- ZBrush Texture Exports