Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
WebP Image
image/webp
WebP
A complete technical comparison of DICOM Run-Length Encoding and WebP Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
WebP wins on browser support
Feature Support
| Feature | DICOM-RLE | WebP |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
WebP Image
image/webp
Extension
.webp
Container
RIFF
Compression
Lossy / Lossless
Algorithm
VP8VP8L
Color Depth
8-bit
Developed by
Google
Released
2010
Magic Bytes
52 49 46 46 XX XX XX XX 57 45 42 50
Browser Support Comparison
| Browser | DICOM-RLE | WebP |
|---|---|---|
Chrome
|
✕ |
✓ 32+
|
Firefox
|
✕ |
✓ 65+
|
Safari
|
✕ |
✓ 14+
|
Edge
|
✕ |
✓ 18+
|
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
WebP
WebP Strengths
- Superior lossy compression — 25–35% smaller than JPEG at equivalent quality
- Supports both animation and full alpha transparency
- Lossless mode available with smaller file sizes than PNG
Limitations
- Slower encoding than JPEG, especially for lossless
- Not supported in Internet Explorer or very old browsers
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
WebP
Use WebP when…
- Websites
- Ecommerce
- Mobile Apps
- CMS Images