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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

TIFF for Facsimile eXtended

image/tiff-fx
TIFF-FX

A complete technical comparison of DICOM Run-Length Encoding and TIFF for Facsimile eXtended — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE TIFF-FX
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
TIFF for Facsimile eXtended
image/tiff-fx
Extension
.tiff.tif
Container TIFF 6.0 Tag Directory Structure
Compression MH / MR / MMR (CCITT Group 3 & 4) / JBIG / JPEG
Algorithm
CCITT Group 3/4JBIGJPEG
Color Depth 1-bit (Monochrome B&W), 8-bit (Grayscale/Color Indexed), 24-bit (RGB Color)
Developed by IETF (Internet Engineering Task Force)
Released 1998
Magic Bytes
49 49 2A 00 (Little-Endian) / 4D 4D 00 2A (Big-Endian)
Full TIFF-FX reference →

Browser Support Comparison

Browser DICOM-RLE TIFF-FX
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
TIFF-FX

TIFF-FX Strengths

  • Provides a universal, standardized format for transmitting multi-page documents over IP networks and email (Internet Fax)
  • Supports highly efficient telecom-centric compression algorithms (MMR, JBIG) that produce very small files for text documents
  • Maintains backwards compatibility with standard TIFF parsers
Limitations
  • Not supported natively by web browsers
  • Requires complex parsing of TIFF IFD tags to differentiate a true TIFF-FX file from a standard TIFF file
  • Usage is slowly declining as traditional faxing is replaced by secure PDF transmission and e-signature platforms

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
TIFF-FX
Use TIFF-FX when…
  • Internet Fax (T.37)
  • Enterprise Fax Servers
  • Document Archiving
  • Telecommunications
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