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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Sigma X3F RAW Image

image/x-sigma-x3f
Sigma-X3F

A complete technical comparison of DICOM Run-Length Encoding and Sigma X3F RAW Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE Sigma-X3F
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Sigma X3F RAW Image
image/x-sigma-x3f
Extension
.x3f
Container Foveon Proprietary Header
Compression Uncompressed / Proprietary Lossless
Algorithm
NoneFoveon Proprietary Huffman-based
Color Depth 12-bit (Per Channel), 14-bit (Per Channel)
Developed by Foveon, Inc. / Sigma Corporation
Released 2002
Magic Bytes
46 4F 56 62
Full Sigma-X3F reference →

Browser Support Comparison

Browser DICOM-RLE Sigma-X3F
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
Sigma-X3F

Sigma-X3F Strengths

  • Provides absolute per-pixel color accuracy without the interpolation artifacts or moiré patterns typical of Bayer-sensor RAW files
  • Unique 'FOVb' magic byte signature prevents accidental misidentification by standard file sniffers, unlike many TIFF-based raw formats
  • Incredible sharpness and detail resolution at the raw sensor level
Limitations
  • Decoding is extremely computationally expensive and completely proprietary, meaning third-party software often struggles to match the color science of Sigma's own (famously slow) Photo Pro application
  • Massive file sizes because it records three complete RGB channels for every single spatial pixel coordinate
  • Zero support in web browsers or standard OS image viewers

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
Sigma-X3F
Use Sigma-X3F when…
  • Professional Digital Photography
  • Sigma / Foveon High-Acuity Imaging
  • Non-destructive RAW Post-Processing
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