Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
Adobe Photoshop Document
image/vnd.adobe.photoshop
PSD
A complete technical comparison of DICOM Run-Length Encoding and Adobe Photoshop Document — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | PSD |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Adobe Photoshop Document
image/vnd.adobe.photoshop
Extension
.psd.psb.pdd
Container
Adobe Photoshop Document (PSD/PSB)
Compression
Uncompressed / RLE (Run-Length Encoding) / ZIP
Algorithm
RLEZIP (with or without prediction)None
Color Depth
1-bit (Bitmap), 8-bit, 16-bit, 32-bit (Float/HDR)
Developed by
Adobe Systems
Released
1990
Magic Bytes
38 42 50 53
Browser Support Comparison
| Browser | DICOM-RLE | PSD |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
PSD
PSD Strengths
- The undisputed global standard for layered raster graphics and non-destructive image editing
- Supports incredibly complex compositions combining raster data, vector shapes, live text, and adjustment layers
- Full support for advanced color spaces (CMYK, Lab, multi-channel) and 32-bit floating-point HDR workflows
Limitations
- Proprietary format: while the specification is published, complete feature-parity is rarely achieved by third-party software (e.g., smart objects and complex layer styles often break)
- Files can reach enormous sizes (gigabytes) due to the preservation of unflattened, high-resolution layer data
- Zero support for native rendering in web browsers or standard mobile image viewers
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
PSD
Use PSD when…
- Professional Photo Retouching
- Digital Painting and Illustration
- UI/UX Design Workflows
- Graphic Design and Print Production