Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
PiCture eXchange
image/x-pcx
PCX
A complete technical comparison of DICOM Run-Length Encoding and PiCture eXchange — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | PCX |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | Yes | ✕ No |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
PiCture eXchange
image/x-pcx
Extension
.pcx
Container
ZSoft Proprietary Header (128 bytes)
Compression
Run-Length Encoding (RLE)
Algorithm
ZSoft RLE
Color Depth
1-bit (Monochrome), 4-bit (16 colors), 8-bit (256 colors), 24-bit (True Color)
Developed by
ZSoft Corporation
Released
1985
Magic Bytes
0A (followed by version, e.g., 0A 05 01 08)
Browser Support Comparison
| Browser | DICOM-RLE | PCX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
PCX
PCX Strengths
- Incredibly simple RLE algorithm makes it very fast to decode, which was historically vital for early 3D video game engines
- Retains crisp, lossless pixel data suitable for pixel art and interface assets
- Well-documented and highly supported by older desktop publishing and image editing software
Limitations
- Extremely inefficient compression by modern standards, producing large file sizes compared to PNG
- Lacks modern imaging features such as alpha channel transparency, EXIF metadata, and color profiles
- Zero support in web browsers; must be converted to PNG for web use
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
PCX
Use PCX when…
- MS-DOS and Early Windows Graphics
- 1990s Video Game Assets (Textures, UI)
- Retro Computing Archival