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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Network FlashPix

image/vnd.net-fpx
Net-FPX

A complete technical comparison of DICOM Run-Length Encoding and Network FlashPix — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE Net-FPX
Transparency (Alpha) ✕ No Yes
Animation Support Yes ✕ No
Progressive Loading ✕ No Yes
HDR Support Yes ✕ No
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Network FlashPix
image/vnd.net-fpx
Extension
.fpx
Container Microsoft OLE Structured Storage (COM)
Compression JPEG (Lossy) / Uncompressed / Single-color (Solid)
Algorithm
JPEGNone
Color Depth 8-bit (Grayscale/Indexed), 24-bit (RGB), 32-bit (CMYK/RGBA)
Developed by Digital Imaging Group (Kodak, HP, Live Picture, Microsoft)
Released 1996
Magic Bytes
D0 CF 11 E0 A1 B1 1A E1
Full Net-FPX reference →

Browser Support Comparison

Browser DICOM-RLE Net-FPX
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
Net-FPX

Net-FPX Strengths

  • Revolutionized web imaging in the late 1990s by proving that massive gigapixel images could be navigated seamlessly over 56k dial-up modems
  • Pioneered the tile-based, multi-resolution pyramid concepts that eventually evolved into modern standards like IIIF (International Image Interoperability Framework)
Limitations
  • Completely obsolete, having been replaced by standard JPEG servers and modern tiling formats like Deep Zoom or JPEG 2000/XR
  • Relied on proprietary Java applets or ActiveX controls to render the tiles dynamically in a web browser
  • Extremely complex to parse server-side due to the heavy OLE filesystem container

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
Net-FPX
Use Net-FPX when…
  • Historical Internet Imaging Protocol (IIP) Streaming
  • Early E-Commerce Deep Zoom Implementations
  • Legacy High-Resolution Image Servers
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