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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Kodak K25 Raw Image

image/x-kodak-k25
Kodak-K25

A complete technical comparison of DICOM Run-Length Encoding and Kodak K25 Raw Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE Kodak-K25
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes ✕ No
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Kodak K25 Raw Image
image/x-kodak-k25
Extension
.k25
Container Proprietary Kodak Raw (TIFF-based variant)
Compression Uncompressed / Proprietary Lossless
Algorithm
Proprietary Kodak Compression
Color Depth 10-bit, 12-bit (Per Channel)
Developed by Eastman Kodak Company
Released 1996
Magic Bytes
Varies (Often resembles TIFF header 49 49 2A 00 or requires proprietary parsing)
Full Kodak-K25 reference →

Browser Support Comparison

Browser DICOM-RLE Kodak-K25
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
Kodak-K25

Kodak-K25 Strengths

  • Historically significant format tied to the first digital camera to adopt CompactFlash memory
  • Preserves original raw sensor data, allowing modern demosaicing algorithms (via LibRaw) to extract much better image quality than 1996-era software could
Limitations
  • Completely obsolete and deeply proprietary, lacking modern raw format features found in DNG
  • Cannot be natively viewed in web browsers or standard operating system image viewers without specialized decoders
  • Subject to misidentification by automated MIME detection libraries due to structural similarities with standard TIFFs

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
Kodak-K25
Use Kodak-K25 when…
  • Vintage Digital Photography Archival
  • Kodak DC25 Camera Restorations
  • Historical Imaging Research
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