Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
JPEG XL
image/jxl
JXL
A complete technical comparison of DICOM Run-Length Encoding and JPEG XL — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
JXL wins on browser support
Feature Support
| Feature | DICOM-RLE | JXL |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | Yes |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
JPEG XL
image/jxl
Extension
.jxl
Container
ISOBMFF / JPEG XL Codestream
Compression
Lossy (VarDCT) / Lossless (Modular)
Algorithm
VarDCT (Variable block-size DCT)Modular (Predictive coding for lossless)
Color Depth
8-bit, 10-bit, 12-bit, 16-bit, 32-bit (Float)
Developed by
Joint Photographic Experts Group (JPEG)
Released
2021
Magic Bytes
FF 0A (Codestream) / 00 00 00 0C 4A 58 4C 20 0D 0A 87 0A (Container)
Browser Support Comparison
| Browser | DICOM-RLE | JXL |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ |
✓ 17+
|
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JXL
JXL Strengths
- Capable of losslessly recompressing legacy JPEG files, saving ~20% space while retaining perfect byte-for-byte restorability
- Highly superior progressive decoding (Saliency-driven), allowing recognizable images to load extremely fast on slow connections
- Outperforms WebP and competes favorably with AVIF, especially at high-fidelity settings and for complex textures/photography
- Royalty-free with an open-source reference implementation (libjxl)
Limitations
- Google's removal of JXL support from Chrome severely hindered its adoption as a universal web standard
- Lack of hardware decoding chips compared to video-derived codecs like AVIF (AV1)
- File parsing logic is complex due to the split between raw codestreams and ISOBMFF containers
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
JXL
Use JXL when…
- High-End Web Delivery (via Safari/Polyfills)
- HDR Photography
- Legacy JPEG Archiving
- Digital Art & Image Storage