Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
JPEG 2000 Part 2 (Extended)
image/jpx
JPX
A complete technical comparison of DICOM Run-Length Encoding and JPEG 2000 Part 2 (Extended) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | JPX |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | Yes |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
JPEG 2000 Part 2 (Extended)
image/jpx
Extension
.jpx.jpf
Container
ISOBMFF / JPX (ISO/IEC 15444-2)
Compression
Lossy / Lossless
Algorithm
Discrete Wavelet Transform (DWT)
Color Depth
8-bit, 16-bit, 32-bit, 38-bit
Developed by
Joint Photographic Experts Group (JPEG)
Released
2002
Magic Bytes
00 00 00 0C 6A 50 20 20 0D 0A 87 0A ... 66 74 79 70 6A 70 78 20
Browser Support Comparison
| Browser | DICOM-RLE | JPX |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JPX
JPX Strengths
- Removes the color space limitations of baseline JP2, adding native support for CMYK, CIE Lab, and custom vendor color spaces
- Supports multiple codestreams in a single file, allowing for rich compositing and animation
- Enables fragmented files where image data and metadata can reside in separate physical files via data references
Limitations
- Extremely complex specification makes full software implementation rare, leading to compatibility issues
- Zero web browser support, rendering it unsuitable for public internet distribution
- Often overkill for standard imaging tasks where baseline JP2 or modern alternatives like AVIF suffice
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
JPX
Use JPX when…
- Prepress & Commercial Printing (CMYK)
- Geospatial Data
- Archival Preservation
- Medical Imaging