Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
JPEG XS Image (HEIF Container)
image/jxsi
JPEG-XS-(HEIF)
A complete technical comparison of DICOM Run-Length Encoding and JPEG XS Image (HEIF Container) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | JPEG-XS-(HEIF) |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
JPEG XS Image (HEIF Container)
image/jxsi
Extension
.jxsi.jxs.hif
Container
HEIF / ISOBMFF (ISO/IEC 23008-12)
Compression
Lossy (Visually Lossless) / Mathematically Lossless
Algorithm
JPEG XS (ISO/IEC 21122-1)
Color Depth
8-bit, 10-bit, 12-bit, 14-bit, 16-bit
Developed by
Joint Photographic Experts Group (JPEG)
Released
2019
Magic Bytes
XX XX XX XX 66 74 79 70 6A 78 73 69
Browser Support Comparison
| Browser | DICOM-RLE | JPEG-XS-(HEIF) |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JPEG-XS-(HEIF)
JPEG-XS-(HEIF) Strengths
- Provides sub-millisecond encoding and decoding latency while retaining visually lossless quality
- Brings the extensive metadata, EXIF, XMP, and color-profiling capabilities of the HEIF container to JPEG XS
- Allows grouping of multiple high-quality JPEG XS frames into a single collection file
Limitations
- Zero web browser compatibility, limiting it entirely to professional and industrial hardware workflows
- Extremely niche adoption compared to standard HEVC-based HEIC or raw JPEG XS codestreams
- Requires custom parsing logic to extract the JPEG XS codestream from the HEIF boxes
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
JPEG-XS-(HEIF)
Use JPEG-XS-(HEIF) when…
- Live Broadcast Infrastructure
- Medical Imaging & Archival
- Video over IP Networks
- Automotive & Drone Systems