Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
JPEG XS Image
image/jxs
JPEG-XS
A complete technical comparison of DICOM Run-Length Encoding and JPEG XS Image — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | JPEG-XS |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
JPEG XS Image
image/jxs
Extension
.jxs
Container
ISOBMFF (ISO/IEC 21122-3) or Raw Codestream
Compression
Lossy (Visually Lossless) / Mathematically Lossless
Algorithm
JPEG XS (Low-complexity wavelet transform)
Color Depth
8-bit, 10-bit, 12-bit, 14-bit, 16-bit
Developed by
Joint Photographic Experts Group (JPEG) / intoPIX
Released
2019
Magic Bytes
FF 10 (Codestream) / XX XX XX XX 66 74 79 70 6A 78 73 20 (ISOBMFF)
Browser Support Comparison
| Browser | DICOM-RLE | JPEG-XS |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JPEG-XS
JPEG-XS Strengths
- Provides sub-millisecond encoding/decoding latency, essential for live production and gaming
- Extremely lightweight, requiring very little CPU, GPU, or FPGA memory to process
- Replaces uncompressed video links (like SDI or HDMI) over standard Ethernet networks with visually lossless quality
Limitations
- Compression ratios are typically much lower (between 2:1 and 10:1) compared to heavy codecs like HEVC or AV1
- Zero support in web browsers or standard consumer devices
- Primarily licensed to hardware manufacturers and professional software ecosystems
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
JPEG-XS
Use JPEG-XS when…
- Live Video Broadcasting (SMPTE ST 2110)
- Video over IP Networks
- Virtual Reality / Augmented Reality (VR/AR)
- Automotive & Drone Cameras