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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

JPEG-LS

image/jls
JPEG-LS

A complete technical comparison of DICOM Run-Length Encoding and JPEG-LS — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE JPEG-LS
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes Yes
EXIF Metadata ✕ No ✕ No
ICC Color Profile Yes ✕ No
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
JPEG-LS
image/jls
Extension
.jls.jl
Container JPEG Bitstream
Compression Lossless / Near-Lossless (Predictive Coding)
Algorithm
LOCO-I (Low Complexity Lossless Compression for Images)Golomb-Rice Coding
Color Depth 8-bit, 12-bit, 16-bit (Per Channel)
Developed by Joint Photographic Experts Group (ISO/ITU-T) & HP Labs
Released 1999
Magic Bytes
FF D8 FF F7
Full JPEG-LS reference →

Browser Support Comparison

Browser DICOM-RLE JPEG-LS
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
JPEG-LS

JPEG-LS Strengths

  • Provides state-of-the-art lossless compression ratios for continuous-tone images, often outperforming Lossless JPEG and JPEG 2000
  • Extremely fast and computationally inexpensive to encode/decode, requiring no complex floating-point math or DCTs
  • Highly resilient in constrained hardware environments, making it ideal for medical equipment and deep-space probes (e.g., Mars rovers)
Limitations
  • Zero native support in web browsers or standard consumer operating systems
  • Lacks the advanced resolution scalability and progressive decoding features found in JPEG 2000
  • Primarily relegated to niche enterprise sectors (healthcare/DICOM and aerospace) rather than consumer adoption

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
JPEG-LS
Use JPEG-LS when…
  • Medical Imaging (DICOM Encapsulation)
  • Space and Planetary Imaging (NASA/ESA)
  • Industrial Machine Vision
  • Scientific Archival Storage
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