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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Image Exchange Format

image/ief
IEF

A complete technical comparison of DICOM Run-Length Encoding and Image Exchange Format — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE IEF
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes ✕ No
EXIF Metadata ✕ No ✕ No
ICC Color Profile Yes ✕ No
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Image Exchange Format
image/ief
Extension
.ief
Container TIFF Class B (TIFF-B)
Compression Lossless (MH, MR, MMR) / Uncompressed
Algorithm
MHMRMMRUncompressed
Color Depth 1-bit (Monochrome)
Developed by IETF Network Fax Working Group
Released 1992
Magic Bytes
49 49 2A 00 (Little-endian) / 4D 4D 00 2A (Big-endian)
Full IEF reference →

Browser Support Comparison

Browser DICOM-RLE IEF
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
IEF

IEF Strengths

  • Provided a standard method for exchanging bi-level fax images during the early days of the Internet
  • Supported multi-page documents
  • Leveraged the highly resilient and well-documented TIFF container
Limitations
  • Completely obsolete and unsupported in modern computing environments
  • Strictly limited to 1-bit monochrome data, lacking color or grayscale capabilities
  • Magic bytes overlap completely with standard TIFF, making specific filetype detection difficult without parsing internal tags

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
IEF
Use IEF when…
  • Legacy Fax Transmissions
  • Early Internet Gateways
  • Archival
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