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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

JPEG 2000 Image Sequence (Obsolete)

image/hsj2
HSJ2

A complete technical comparison of DICOM Run-Length Encoding and JPEG 2000 Image Sequence (Obsolete) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE HSJ2
Transparency (Alpha) ✕ No Yes
Animation Support Yes Yes
Progressive Loading ✕ No Yes
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
JPEG 2000 Image Sequence (Obsolete)
image/hsj2
Extension
.hsj2
Container HEIF / ISOBMFF (ISO/IEC 15444-16 Obsolete)
Compression Lossy / Lossless
Algorithm
Motion JPEG 2000 (ISO/IEC 15444-3)
Color Depth 8-bit, 10-bit, 12-bit, 16-bit
Developed by ISO/IEC JTC 1 / ITU-T
Released 2019
Magic Bytes
XX XX XX XX 66 74 79 70 68 73 6A 32
Full HSJ2 reference →

Browser Support Comparison

Browser DICOM-RLE HSJ2
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
HSJ2

HSJ2 Strengths

  • Historically attempted to combine Motion JPEG 2000 sequences with the flexible metadata capabilities of the HEIF container
  • Supported mathematically lossless compression and scalable wavelet decoding
Limitations
  • Officially deprecated by the standardization body (ISO/IEC JTC 1)
  • Completely superseded by image/hej2k, rendering hsj2 files obsolete for any new development or archiving
  • Zero web browser compatibility and negligible modern software support

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
HSJ2
Use HSJ2 when…
  • Legacy Archival
  • Deprecated Workflows
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