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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

JPEG 2000 Image (HEIF Container)

image/hej2k
HEJ2K

A complete technical comparison of DICOM Run-Length Encoding and JPEG 2000 Image (HEIF Container) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE HEJ2K
Transparency (Alpha) ✕ No Yes
Animation Support Yes ✕ No
Progressive Loading ✕ No Yes
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
JPEG 2000 Image (HEIF Container)
image/hej2k
Extension
.hej2
Container HEIF / ISOBMFF (ISO/IEC 15444-16)
Compression Lossy / Lossless
Algorithm
JPEG 2000HTJ2K
Color Depth 8-bit, 10-bit, 12-bit, 16-bit
Developed by ISO/IEC JTC 1 / ITU-T
Released 2019
Magic Bytes
XX XX XX XX 66 74 79 70 6A 32 6B 69
Full HEJ2K reference →

Browser Support Comparison

Browser DICOM-RLE HEJ2K
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
HEJ2K

HEJ2K Strengths

  • Brings the extensive capabilities of the HEIF container (like EXIF/XMP, thumbnails, and depth maps) to JPEG 2000
  • Supports mathematically lossless compression via wavelet transformation
  • High scalability and progressive decoding out of the box
Limitations
  • Extremely limited software support outside of niche industries
  • Zero native compatibility with web browsers
  • High computational complexity compared to simpler formats like JPEG or PNG

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
HEJ2K
Use HEJ2K when…
  • Medical Imaging
  • Geospatial Data
  • Scientific Archiving
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