Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
HEVC Image Sequence (HEIF Container)
image/heic-sequence
HEIC-Sequence
A complete technical comparison of DICOM Run-Length Encoding and HEVC Image Sequence (HEIF Container) — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
HEIC-Sequence wins on browser support
Feature Support
| Feature | DICOM-RLE | HEIC-Sequence |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
HEVC Image Sequence (HEIF Container)
image/heic-sequence
Extension
.heics.heic
Container
HEIF / ISOBMFF (ISO/IEC 14496-12)
Compression
Lossy / Lossless
Algorithm
HEVC (H.265)
Color Depth
8-bit, 10-bit, 12-bit, 16-bit
Developed by
Moving Picture Experts Group (MPEG) / Apple
Released
2017
Magic Bytes
XX XX XX XX 66 74 79 70 68 65 76 63
Browser Support Comparison
| Browser | DICOM-RLE | HEIC-Sequence |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ |
✓ 11+
|
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
HEIC-Sequence
HEIC-Sequence Strengths
- Incredibly efficient storage for bursts and short animations compared to GIF or motion JPEG
- Supports 16-bit color, HDR, and alpha channel transparency across all frames
- Shares frame data blocks, meaning the base image and animation data are heavily optimized for space
Limitations
- Zero support in web browsers outside the Apple ecosystem (Chrome, Firefox, Edge do not support it)
- Heavily encumbered by HEVC patent pools, hindering open-source adoption
- Complex container structure makes parsing and decoding difficult without specialized libraries
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
HEIC-Sequence
Use HEIC-Sequence when…
- Apple Live Photos
- Burst Photography
- High-Quality Animations
- Cinemagraphs