Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
Global Graphics Page Graphics Buffer
image/vnd.globalgraphics.pgb
Harlequin-PGB
A complete technical comparison of DICOM Run-Length Encoding and Global Graphics Page Graphics Buffer — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | Harlequin-PGB |
|---|---|---|
| Transparency (Alpha) | ✕ No | ✕ No |
| Animation Support | Yes | ✕ No |
| Progressive Loading | ✕ No | ✕ No |
| HDR Support | Yes | ✕ No |
| EXIF Metadata | ✕ No | ✕ No |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Global Graphics Page Graphics Buffer
image/vnd.globalgraphics.pgb
Extension
.pgb
Container
Proprietary Harlequin Raster Container
Compression
Uncompressed / Run-Length Encoding (RLE)
Algorithm
Proprietary RLENone
Color Depth
1-bit (Monochrome Separations), 8-bit (Grayscale), 8-bit/10-bit (Contone), CMYK / N-Color Spot Channels
Developed by
Global Graphics Software (Hybrid Software Group)
Released
1990s
Magic Bytes
Unknown (Proprietary Harlequin Header)
Browser Support Comparison
| Browser | DICOM-RLE | Harlequin-PGB |
|---|---|---|
Chrome
|
✕ | ✕ |
Firefox
|
✕ | ✕ |
Safari
|
✕ | ✕ |
Edge
|
✕ | ✕ |
IE (Legacy)
|
✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
Harlequin-PGB
Harlequin-PGB Strengths
- Unlike generic 1-bit TIFFs, PGB files inherently encapsulate vital print-job metadata within their headers (e.g., job name, page number, separation colors, screening angles)
- Highly optimized for ultra-fast viewing and processing within professional printing workflows
Limitations
- Completely proprietary and closed-source, locking its usage strictly to Harlequin-powered RIP environments
- Zero support in standard desktop operating systems, web browsers, or consumer image editing software like Photoshop or GIMP
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
Harlequin-PGB
Use Harlequin-PGB when…
- Commercial Printing Output
- Computer-to-Plate (CTP) Manufacturing
- Prepress Soft Proofing (e.g., FirstPROOF)
- Harlequin RIP Spooling Pipelines