Free webp to jpg
Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

FlashPix

image/vnd.fpx
FPX

A complete technical comparison of DICOM Run-Length Encoding and FlashPix — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE FPX
Transparency (Alpha) ✕ No Yes
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes ✕ No
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
FlashPix
image/vnd.fpx
Extension
.fpx
Container Microsoft OLE Structured Storage (COM)
Compression JPEG (Lossy) / Uncompressed / Single-color (Solid)
Algorithm
JPEGNone
Color Depth 8-bit (Grayscale/Indexed), 24-bit (RGB), 32-bit (CMYK/RGBA)
Developed by Eastman Kodak, Microsoft, Hewlett-Packard, Live Picture
Released 1996
Magic Bytes
D0 CF 11 E0 A1 B1 1A E1
Full FPX reference →

Browser Support Comparison

Browser DICOM-RLE FPX
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
FPX

FPX Strengths

  • Allowed early, low-RAM computers to view and edit massive, high-resolution digital photos instantly by only loading the needed tiles and resolutions
  • Pioneered the multi-resolution pyramid and tiling concepts heavily used today in modern deep-zoom and web mapping applications (like Google Maps)
Limitations
  • Completely obsolete and unsupported by modern web browsers or operating systems
  • Uses the complex, proprietary Microsoft OLE container format, making it incredibly difficult to parse or extract data from without dedicated legacy libraries
  • Prone to being misidentified by MIME sniffers as an old Microsoft Office document

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
FPX
Use FPX when…
  • Legacy Digital Photography
  • Kodak Picture CDs (Historical)
  • Early High-Resolution Image Viewers
Share this comparison