Image MIME Reference
DICOM-RLE
DICOM Run-Length Encoding
image/dicom-rle
VS
Free Lossless Image Format
image/flif
FLIF
A complete technical comparison of DICOM Run-Length Encoding and Free Lossless Image Format — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.
Equal browser support
Feature Support
| Feature | DICOM-RLE | FLIF |
|---|---|---|
| Transparency (Alpha) | ✕ No | Yes |
| Animation Support | Yes | Yes |
| Progressive Loading | ✕ No | Yes |
| HDR Support | Yes | Yes |
| EXIF Metadata | ✕ No | Yes |
| ICC Color Profile | Yes | Yes |
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container
DICOM (PS3.10)
Compression
Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth
8-bit, 16-bit, 24-bit
Developed by
National Electrical Manufacturers Association (NEMA) / ACR
Released
1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Free Lossless Image Format
image/flif
Extension
.flif
Container
FLIF Bitstream
Compression
Lossless (MANIAC Entropy Coding)
Algorithm
MANIAC (Meta-Adaptive Near-zero Integer Arithmetic Coding)
Color Depth
1-bit to 16-bit (Per Channel), Grayscale, RGB, RGBA, CMYK
Developed by
Jon Sneyers and Pieter Wuille (Cloudinary)
Released
2015
Magic Bytes
46 4C 49 46
Browser Support Comparison
| Browser | DICOM-RLE | FLIF |
|---|---|---|
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
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✕ | ✕ |
DICOM-RLE
DICOM-RLE Strengths
- Guarantees lossless preservation of critical medical data necessary for diagnostics
- Extremely robust metadata structure containing patient information, modality, and spatial geometry
- Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
- RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
- Zero support in web browsers or standard consumer image viewers
- Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
FLIF
FLIF Strengths
- Achieves some of the highest lossless compression ratios ever developed for raster images
- Incredible progressive decoding allows an image to be highly recognizable even after only 5% of the file has been downloaded
- Supports animations and complex alpha channels losslessly
Limitations
- Officially abandoned in favor of JPEG XL
- Zero native support in web browsers or standard operating system previewers
- Encoding speed can be significantly slower than standard PNG or WebP compression
When to choose which format
DICOM-RLE
Use DICOM-RLE when…
- Medical Imaging
- Ultrasound
- X-Rays / CT / MRI
- PACS Archives
FLIF
Use FLIF when…
- Archival of Uncompressed Image Assets
- Bandwidth-Constrained Progressive Image Loading (Historical)
- Medical and Scientific Imaging Storage