Free webp to jpg
Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Free Lossless Image Format

image/flif
FLIF

A complete technical comparison of DICOM Run-Length Encoding and Free Lossless Image Format — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE FLIF
Transparency (Alpha) ✕ No Yes
Animation Support Yes Yes
Progressive Loading ✕ No Yes
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes Yes
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Free Lossless Image Format
image/flif
Extension
.flif
Container FLIF Bitstream
Compression Lossless (MANIAC Entropy Coding)
Algorithm
MANIAC (Meta-Adaptive Near-zero Integer Arithmetic Coding)
Color Depth 1-bit to 16-bit (Per Channel), Grayscale, RGB, RGBA, CMYK
Developed by Jon Sneyers and Pieter Wuille (Cloudinary)
Released 2015
Magic Bytes
46 4C 49 46
Full FLIF reference →

Browser Support Comparison

Browser DICOM-RLE FLIF
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
FLIF

FLIF Strengths

  • Achieves some of the highest lossless compression ratios ever developed for raster images
  • Incredible progressive decoding allows an image to be highly recognizable even after only 5% of the file has been downloaded
  • Supports animations and complex alpha channels losslessly
Limitations
  • Officially abandoned in favor of JPEG XL
  • Zero native support in web browsers or standard operating system previewers
  • Encoding speed can be significantly slower than standard PNG or WebP compression

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
FLIF
Use FLIF when…
  • Archival of Uncompressed Image Assets
  • Bandwidth-Constrained Progressive Image Loading (Historical)
  • Medical and Scientific Imaging Storage
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