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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Flexible Image Transport System

image/fits
FITS

A complete technical comparison of DICOM Run-Length Encoding and Flexible Image Transport System — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE FITS
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes Yes
EXIF Metadata ✕ No ✕ No
ICC Color Profile Yes ✕ No
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Flexible Image Transport System
image/fits
Extension
.fits.fit.fts
Container FITS
Compression Uncompressed / Tile Compressed (Rice, GZIP)
Algorithm
UncompressedRiceGZIPHcompress
Color Depth 8-bit, 16-bit, 32-bit, 64-bit (Float/Double)
Developed by IAU FITS Working Group / NASA
Released 1981
Magic Bytes
53 49 4D 50 4C 45 20 20 3D 20
Full FITS reference →

Browser Support Comparison

Browser DICOM-RLE FITS
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
FITS

FITS Strengths

  • The undisputed global standard for archiving and sharing astronomical data
  • Self-documenting: Headers are written in plain ASCII, ensuring data is readable decades later regardless of software
  • Supports incredibly high dynamic range, N-dimensional arrays, and complex binary tables
Limitations
  • No support in standard consumer software or web browsers
  • Uncompressed raw FITS files from modern telescopes can be excessively large
  • Does not use standard metadata models like EXIF or XMP, requiring specialized parsers

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
FITS
Use FITS when…
  • Astronomy & Astrophysics
  • Space Telescope Data (Hubble, JWST)
  • Scientific Data Archiving
  • Spectroscopy
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