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Image MIME Reference
DICOM-RLE

DICOM Run-Length Encoding

image/dicom-rle
VS

Epson Raw Format

image/x-epson-erf
Epson-ERF

A complete technical comparison of DICOM Run-Length Encoding and Epson Raw Format — covering compression, feature support, browser compatibility, magic bytes, and when to choose each format.

Equal browser support

Feature Support

Feature DICOM-RLE Epson-ERF
Transparency (Alpha) ✕ No ✕ No
Animation Support Yes ✕ No
Progressive Loading ✕ No ✕ No
HDR Support Yes Yes
EXIF Metadata ✕ No Yes
ICC Color Profile Yes ✕ No
DICOM Run-Length Encoding
image/dicom-rle
Extension
.dcm.dicom
Container DICOM (PS3.10)
Compression Lossless (RLE)
Algorithm
Run-Length Encoding (RLE)
Color Depth 8-bit, 16-bit, 24-bit
Developed by National Electrical Manufacturers Association (NEMA) / ACR
Released 1993
Magic Bytes
44 49 43 4D (at byte offset 128)
Full DICOM-RLE reference →
Epson Raw Format
image/x-epson-erf
Extension
.erf
Container TIFF/EP
Compression Uncompressed / Lossless JPEG (ITU-T81)
Algorithm
NoneLossless JPEG
Color Depth 12-bit (Per Channel)
Developed by Seiko Epson Corporation
Released 2004
Magic Bytes
49 49 2A 00 or 4D 4D 00 2A
Full Epson-ERF reference →

Browser Support Comparison

Browser DICOM-RLE Epson-ERF
Chrome Chrome
Firefox Firefox
Safari Safari
Edge Edge
IE IE (Legacy)
DICOM-RLE

DICOM-RLE Strengths

  • Guarantees lossless preservation of critical medical data necessary for diagnostics
  • Extremely robust metadata structure containing patient information, modality, and spatial geometry
  • Faster to encode and decode than complex compression schemes like JPEG 2000
Limitations
  • RLE compression offers very low compression ratios compared to modern codecs like JPEG-LS or JPEG 2000
  • Zero support in web browsers or standard consumer image viewers
  • Strict data privacy regulations (HIPAA/GDPR) make handling DICOM files complex due to embedded PHI
Epson-ERF

Epson-ERF Strengths

  • Preserves original raw sensor data, allowing extreme recovery of highlights and shadows compared to in-camera JPEGs
  • Utilizes the standard TIFF container structure, making it relatively easy for open-source software (like dcraw and LibRaw) to parse and decode
Limitations
  • Completely obsolete proprietary format tied to a defunct line of digital cameras
  • Requires parsing EXIF metadata to differentiate it from standard TIFF files programmatically
  • Cannot be natively viewed in web browsers or standard operating system image viewers without specialized codecs

When to choose which format

DICOM-RLE
Use DICOM-RLE when…
  • Medical Imaging
  • Ultrasound
  • X-Rays / CT / MRI
  • PACS Archives
Epson-ERF
Use Epson-ERF when…
  • Vintage Digital Photography (Epson R-D1)
  • Non-destructive Image Post-Processing
  • Raw Imaging Archival
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